The world’s leading pan-isotype therapeutic antibody company

We are a clinical-stage company, pioneering radically new antibody therapeutics for oncology. 

We have unique and proprietary expertise in the discovery and development of IgE, IgA and IgG-based therapeutics with each isotype possessing differentiated immune effector function.

Evolved to treat parasitic infection, IgE has significant activity against various tumour types by activating myeloid cells and T cells thereby warming up the tumour micro-environment. IgA’s anti-cancer potential is mediated by the activation of neutrophils. The distinct activity profiles of each isotype allow us to select the most appropriate isotype for a given cancer.

Our lead clinical candidate, MOv18 IgE, targets folate receptor alpha (FRα). It has successfully completed a phase I trial in ovarian cancer and was found to be safe and well tolerated with early signs of clinical activity. A phase Ib trial of MOv18 IgE in platinum-resistant ovarian cancer (PROC) is underway.

Epsilogen has created a number of platforms based on its expertise with the IgE, IgA and IgG isotypes including bispecific IgE and IgEG antibodies.

Find out more about our business

Management Team

Tim Wilson, PhD.

Chief Executive Officer

Kevin FitzGerald

Chief Scientific Officer

Cristina Oliva

Chief Medical Officer

Nick Robbins-Cherry

Chief Financial Officer

Elizabeth Hardaker

Chief Translational Science Officer

Leanne Partington

VP of Product Development

Andrew Calam

VP of Clinical Operations

Board of Directors

Tim Wilson, PhD.

Chief Executive Officer

Pete Finan

Non-Executive Chairman

Marianne Uteng

Board Member

Marianne Bjørdal

Board Member

Alek Safarian

Board Member

Emma Johnson

Board Member

Sonia Gulati

Board Member

Advisers

Robert Coleman

Clinical Advisor

Susana Banerjee

Clinical Advisor

Thomas Herzog

Clinical Advisor

Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.